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Misfolding of CasBrE SU is reversed by interactions with 4070A Env: implications for gammaretroviral neuropathogenesis

BACKGROUND: CasBrE is a neurovirulent murine leukemia virus (MLV) capable of inducing paralytic disease with associated spongiform neurodegeneration. The neurovirulence of this virus has been genetically mapped to the surface expressed subunit (SU) of the env gene. However, CasBrE SU synthesized in...

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Détails bibliographiques
Auteurs principaux: Li, Ying, Lynch, William P
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998453/
https://ncbi.nlm.nih.gov/pubmed/21054857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-93
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