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Misfolding of CasBrE SU is reversed by interactions with 4070A Env: implications for gammaretroviral neuropathogenesis

BACKGROUND: CasBrE is a neurovirulent murine leukemia virus (MLV) capable of inducing paralytic disease with associated spongiform neurodegeneration. The neurovirulence of this virus has been genetically mapped to the surface expressed subunit (SU) of the env gene. However, CasBrE SU synthesized in...

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Detalhes bibliográficos
Main Authors: Li, Ying, Lynch, William P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998453/
https://ncbi.nlm.nih.gov/pubmed/21054857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-93
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