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Unique N-Linked Glycosylation of CasBrE Env Influences Its Stability, Processing, and Viral Infectivity but Not Its Neurotoxicity

The envelope protein (Env) from the CasBrE murine leukemia virus (MLV) can cause acute spongiform neurodegeneration analogous to that induced by prions. Upon central nervous system (CNS) infection, Env is expressed as multiple isoforms owing to differential asparagine (N)-linked glycosylation. Becau...

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Detalhes bibliográficos
Main Authors: Renszel, Krystal M., Traister, Russell S., Lynch, William P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719805/
https://ncbi.nlm.nih.gov/pubmed/23698308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00392-13
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