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Unique N-Linked Glycosylation of CasBrE Env Influences Its Stability, Processing, and Viral Infectivity but Not Its Neurotoxicity

The envelope protein (Env) from the CasBrE murine leukemia virus (MLV) can cause acute spongiform neurodegeneration analogous to that induced by prions. Upon central nervous system (CNS) infection, Env is expressed as multiple isoforms owing to differential asparagine (N)-linked glycosylation. Becau...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Renszel, Krystal M., Traister, Russell S., Lynch, William P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719805/
https://ncbi.nlm.nih.gov/pubmed/23698308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00392-13
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