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Unique N-Linked Glycosylation of CasBrE Env Influences Its Stability, Processing, and Viral Infectivity but Not Its Neurotoxicity
The envelope protein (Env) from the CasBrE murine leukemia virus (MLV) can cause acute spongiform neurodegeneration analogous to that induced by prions. Upon central nervous system (CNS) infection, Env is expressed as multiple isoforms owing to differential asparagine (N)-linked glycosylation. Becau...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3719805/ https://ncbi.nlm.nih.gov/pubmed/23698308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00392-13 |
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