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TRPC6 channels stimulated by angiotensin II are inhibited by TRPC1/C5 channel activity through a Ca(2+)- and PKC-dependent mechanism in native vascular myocytes

The present work investigated interactions between TRPC1/C5 and TRPC6 cation channel activities evoked by angiotensin II (Ang II) in native rabbit mesenteric artery vascular smooth muscle cells (VSMCs). In low intracellular Ca(2+) buffering conditions (0.1 mm BAPTA), 1 nm and 10 nm Ang II activated...

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Detalles Bibliográficos
Main Authors: Shi, J, Ju, M, Saleh, S N, Albert, A P, Large, W A
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998219/
https://ncbi.nlm.nih.gov/pubmed/20660561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.194621
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