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Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo
Transient maintenance of a pluripotent embryonic cell population followed by the onset of multi-lineage commitment is a fundamental aspect of development. However, molecular regulation of this transition is not well characterized in vivo. Here, we demonstrate that the nuclear protein Geminin is requ...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Company of Biologists
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2998164/ https://ncbi.nlm.nih.gov/pubmed/21098561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.059824 |
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