MST1 Promotes Apoptosis through Phosphorylation of Histone H2AX

MST1 (mammalian STE20-like kinase 1) is a serine/threonine kinase that is cleaved and activated by caspases during apoptosis. Overexpression of MST1 induces apoptotic morphological changes such as chromatin condensation, but the mechanism is not clear. Here we show that MST1 induces apoptotic chroma...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Wen, Weihong, Zhu, Feng, Zhang, Jishuai, Keum, Young-Sam, Zykova, Tatyana, Yao, Ke, Peng, Cong, Zheng, Duo, Cho, Yong-Yeon, Ma, Wei-ya, Bode, Ann M., Dong, Zigang
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998151/
https://ncbi.nlm.nih.gov/pubmed/20921231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.151753
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares