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Role for Transcription Factor TFII-I in the Suppression Of SSeCKS/Gravin/Akap12 Transcription by Src
The SSeCKS/Gravin/AKAP12 gene, encoding a kinase scaffolding protein with metastasis-suppressing activity, is transcriptionally downregulated in Src-transformed cells through the recruitment of HDAC1 to a Src-responsive proximal promoter site charged with Sp1, Sp3 and USF1. However, the ectopic expr...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2997892/ https://ncbi.nlm.nih.gov/pubmed/20568114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25524 |
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