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Suppression of Tumor and Metastasis Progression through the Scaffolding Functions of SSeCKS/Gravin/AKAP12
Scaffolding proteins such as SSeCKS/Gravin/AKAP12 (“AKAP12”) are thought to control oncogenic signaling pathways by regulating key mediators in a spatiotemporal manner. The downregulation of AKAP12 in many human cancers, often associated with promoter hypermethylation, or the loss of its locus at 6q...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3908683/ https://ncbi.nlm.nih.gov/pubmed/22684366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-012-9360-1 |
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