Rb-dependent cellular senescence, multinucleation and susceptibility to oncogenic transformation through PKC scaffolding by SSeCKS/AKAP12

A subset of AKAPs (A Kinase Anchoring Proteins) regulate signaling and cytoskeletal pathways through the spaciotemporal scaffolding of multiple protein kinases (PK), such as PKC and PKA, and associations with the plasma membrane and the actin-based cytoskeleton. SSeCKS/Gravin/Akap12 expression is se...

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Main Authors: Akakura, Shin, Nochajski, Peter, Gao, Lingqiu, Sotomayor, Paul, Matsui, Sei-ichi, Gelman, Irwin H
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048035/
https://ncbi.nlm.nih.gov/pubmed/21099353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.23.13974
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