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Suppression of Tumor and Metastasis Progression through the Scaffolding Functions of SSeCKS/Gravin/AKAP12

Scaffolding proteins such as SSeCKS/Gravin/AKAP12 (“AKAP12”) are thought to control oncogenic signaling pathways by regulating key mediators in a spatiotemporal manner. The downregulation of AKAP12 in many human cancers, often associated with promoter hypermethylation, or the loss of its locus at 6q...

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Autor principal: Gelman, Irwin H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908683/
https://ncbi.nlm.nih.gov/pubmed/22684366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-012-9360-1
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