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Role for Transcription Factor TFII-I in the Suppression Of SSeCKS/Gravin/Akap12 Transcription by Src

The SSeCKS/Gravin/AKAP12 gene, encoding a kinase scaffolding protein with metastasis-suppressing activity, is transcriptionally downregulated in Src-transformed cells through the recruitment of HDAC1 to a Src-responsive proximal promoter site charged with Sp1, Sp3 and USF1. However, the ectopic expr...

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書目詳細資料
Main Authors: Bu, Yahao, Gao, Lingqiu, Gelman, Irwin H.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997892/
https://ncbi.nlm.nih.gov/pubmed/20568114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25524
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