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Enhanced Capillary Amyloid Angiopathy Associated Pathology in Tg-SwDI Mice with Deleted Nitric Oxide Synthase 2

BACKGROUND: Cerebral amyloid angiopathy (CAA)-type 1 is characterized by amyloid β-protein (Aβ) deposition along cerebral capillaries and is accompanied by perivascular neuroinflammation and accumulation of phospho-tau protein. Tg-SwDI mice recapitulate capillary amyloid deposition and associated ne...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Van Nostrand, William E., Xu, Feng, Rozemuller, Annemieke J.M., Colton, Carol A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997647/
https://ncbi.nlm.nih.gov/pubmed/20876489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.110.595272
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