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AGGREGATION MODULATING ELEMENTS IN MUTANT HUMAN SUPEROXIDE DISMUTASE 1(†)

Mutations in superoxide dismutase 1 (SOD1) cause some forms of familial amyotrophic lateral sclerosis (fALS). Affected tissues of patients and transgenic mouse models of the disease accumulate misfolded and aggregated forms of the mutant protein. In the present study we have identified specific sequ...

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Detalhes bibliográficos
Main Authors: Karch, Celeste M., Borchelt, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997613/
https://ncbi.nlm.nih.gov/pubmed/20682279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.07.027
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