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AGGREGATION MODULATING ELEMENTS IN MUTANT HUMAN SUPEROXIDE DISMUTASE 1(†)

Mutations in superoxide dismutase 1 (SOD1) cause some forms of familial amyotrophic lateral sclerosis (fALS). Affected tissues of patients and transgenic mouse models of the disease accumulate misfolded and aggregated forms of the mutant protein. In the present study we have identified specific sequ...

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Hlavní autoři: Karch, Celeste M., Borchelt, David R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997613/
https://ncbi.nlm.nih.gov/pubmed/20682279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.07.027
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