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AGGREGATION MODULATING ELEMENTS IN MUTANT HUMAN SUPEROXIDE DISMUTASE 1(†)

Mutations in superoxide dismutase 1 (SOD1) cause some forms of familial amyotrophic lateral sclerosis (fALS). Affected tissues of patients and transgenic mouse models of the disease accumulate misfolded and aggregated forms of the mutant protein. In the present study we have identified specific sequ...

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Bibliografiske detaljer
Main Authors: Karch, Celeste M., Borchelt, David R.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997613/
https://ncbi.nlm.nih.gov/pubmed/20682279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.07.027
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