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AGGREGATION MODULATING ELEMENTS IN MUTANT HUMAN SUPEROXIDE DISMUTASE 1(†)

Mutations in superoxide dismutase 1 (SOD1) cause some forms of familial amyotrophic lateral sclerosis (fALS). Affected tissues of patients and transgenic mouse models of the disease accumulate misfolded and aggregated forms of the mutant protein. In the present study we have identified specific sequ...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Karch, Celeste M., Borchelt, David R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997613/
https://ncbi.nlm.nih.gov/pubmed/20682279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.07.027
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