The Effect of Cell Cycle Synchronization on Tumor Sensitivity to Reovirus Oncolysis

The potential for increased sensitivity of tumor cells to oncolytic reovirus by altering the normal cell cycle using clinically available pharmacological agents was investigated. B16.F10 mouse melanoma cells were partially synchronized with hydroxyurea, thymidine, or by mitotic shake-off. Cell survi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Heinemann, Lucy, Simpson, Guy R, Annels, Nicola E, Vile, Richard, Melcher, Alan, Prestwich, Robin, Harrington, Kevin J, Pandha, Hardev S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2010
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997589/
https://ncbi.nlm.nih.gov/pubmed/20842107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.189
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