The Effect of Cell Cycle Synchronization on Tumor Sensitivity to Reovirus Oncolysis

The potential for increased sensitivity of tumor cells to oncolytic reovirus by altering the normal cell cycle using clinically available pharmacological agents was investigated. B16.F10 mouse melanoma cells were partially synchronized with hydroxyurea, thymidine, or by mitotic shake-off. Cell survi...

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Bibliografische gegevens
Hoofdauteurs: Heinemann, Lucy, Simpson, Guy R, Annels, Nicola E, Vile, Richard, Melcher, Alan, Prestwich, Robin, Harrington, Kevin J, Pandha, Hardev S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2010
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997589/
https://ncbi.nlm.nih.gov/pubmed/20842107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.189
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