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The Effect of Cell Cycle Synchronization on Tumor Sensitivity to Reovirus Oncolysis
The potential for increased sensitivity of tumor cells to oncolytic reovirus by altering the normal cell cycle using clinically available pharmacological agents was investigated. B16.F10 mouse melanoma cells were partially synchronized with hydroxyurea, thymidine, or by mitotic shake-off. Cell survi...
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| Main Authors: | , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Nature Publishing Group
2010
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2997589/ https://ncbi.nlm.nih.gov/pubmed/20842107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.189 |
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