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Replication Strategies for Rare Variant Complex Trait Association Studies via Next-Generation Sequencing
There is solid evidence that complex traits can be caused by rare variants. Next-generation sequencing technologies are powerful tools for mapping rare variants. Confirmation of significant findings in stage 1 through replication in an independent stage 2 sample is necessary for association studies....
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Elsevier
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2997372/ https://ncbi.nlm.nih.gov/pubmed/21129725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2010.10.025 |
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