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Intracellular calcium-release and protein kinase C-activation stimulate sonic hedgehog gene expression during gastric acid secretion
INTRODUCTION: Hypochlorhydria during Helicobacter pylori infection inhibits gastric Shh expression. We investigated whether acid-secretory mechanisms regulate Shh gene expression through Ca2(+)(i)-dependent protein kinase C (PKC) or cAMP-dependent protein kinase A (PKA)-activation. METHOD: We blocke...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2997213/ https://ncbi.nlm.nih.gov/pubmed/20816837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.08.047 |
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