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DNA methylation status of nuclear-encoded mitochondrial genes underlies the tissue-dependent mitochondrial functions

BACKGROUND: Mitochondria are semi-autonomous, semi-self-replicating organelles harboring their own DNA (mitochondrial DNA, mtDNA), and their dysregulation is involved in the development of various diseases. While mtDNA does not generally undergo epigenetic modifications, almost all mitochondrial pro...

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Bibliografiset tiedot
Päätekijät: Takasugi, Masaki, Yagi, Shintaro, Hirabayashi, Keiji, Shiota, Kunio
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996977/
https://ncbi.nlm.nih.gov/pubmed/20723256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-481
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