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DNA methylation status of nuclear-encoded mitochondrial genes underlies the tissue-dependent mitochondrial functions
BACKGROUND: Mitochondria are semi-autonomous, semi-self-replicating organelles harboring their own DNA (mitochondrial DNA, mtDNA), and their dysregulation is involved in the development of various diseases. While mtDNA does not generally undergo epigenetic modifications, almost all mitochondrial pro...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996977/ https://ncbi.nlm.nih.gov/pubmed/20723256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-481 |
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