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Apoptotic caspases regulate induction of iPS cells from human fibroblasts

The molecular mechanisms involved in the derivation of induced pluripotent stem cells (iPSCs) from differentiated cells are poorly understood. Here we report that caspases 3 and 8, two proteases associated with apoptotic cell death, play critical roles in induction of iPSCs from human fibroblasts. A...

詳細記述

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書誌詳細
主要な著者: Li, Fang, He, Zhimin, Shen, Jingping, Huang, Qian, Li, Wenrong, Liu, Xinjian, He, Yujun, Wolf, Frank, Li, Chuan-Yuan
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996867/
https://ncbi.nlm.nih.gov/pubmed/20887956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.09.003
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