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Apoptotic caspases regulate induction of iPS cells from human fibroblasts
The molecular mechanisms involved in the derivation of induced pluripotent stem cells (iPSCs) from differentiated cells are poorly understood. Here we report that caspases 3 and 8, two proteases associated with apoptotic cell death, play critical roles in induction of iPSCs from human fibroblasts. A...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996867/ https://ncbi.nlm.nih.gov/pubmed/20887956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.09.003 |
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