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Caspase 3 promotes genetic instability and carcinogenesis

Apoptosis is typically considered an anti-oncogenic process since caspase activation can promote the elimination of genetically unstable or damaged cells. We report that a central effector of apoptosis, caspase 3, facilitates, rather than suppresses, chemical and radiation-induced genetic instabilit...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Liu, Xinjian, He, Yujun, Li, Fang, Huang, Qian, Kato, Takamitsu A., Hall, Russell P, Li, Chuan-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408780/
https://ncbi.nlm.nih.gov/pubmed/25866249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.03.003
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