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Caspase 3 promotes genetic instability and carcinogenesis
Apoptosis is typically considered an anti-oncogenic process since caspase activation can promote the elimination of genetically unstable or damaged cells. We report that a central effector of apoptosis, caspase 3, facilitates, rather than suppresses, chemical and radiation-induced genetic instabilit...
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| Опубликовано в: : | Mol Cell |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408780/ https://ncbi.nlm.nih.gov/pubmed/25866249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.03.003 |
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