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A Chemical Platform for Improved Induction of Human iPS Cells

The slow kinetics and low efficiency of reprogramming methods to generate human induced pluripotent stem cells (iPSCs) impose major limitations on their utility in biomedical applications. Here we describe a chemical approach that dramatically improves (>200 fold) the efficiency of iPSC generatio...

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Detalhes bibliográficos
Main Authors: Lin, Tongxiang, Ambasudhan, Rajesh, Yuan, Xu, Li, Wenlin, Hilcove, Simon, Abujarour, Ramzey, Lin, Xiangyi, Hahm, Heung Sik, Hao, Ergeng, Hayek, Alberto, Ding, Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724527/
https://ncbi.nlm.nih.gov/pubmed/19838168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1393
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