p38 Mitogen-Activated Protein Kinase (MAPK) Increases Arginase Activity and Contributes to Endothelial Dysfunction in Corpora Cavernosa from Angiotensin-II Treated Mice

INTRODUCTION: Angiotensin II (AngII) activates p38 mitogen-activated protein kinase (MAPK) and elevates arginase activity in endothelial cells. Upregulation of arginase activity has been implicated in endothelial dysfunction by reducing NO bioavailability. However, signaling pathways activated by An...

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Main Authors: Toque, Haroldo A., Romero, Maritza J., Tostes, Rita C., Shatanawi, Alia, Chandra, Surabhi, Carneiro, Zidonia N., Inscho, Edward W., Webb, R. Clinton, Caldwell, Ruth B., Caldwell, R. William
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996466/
https://ncbi.nlm.nih.gov/pubmed/20807329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1743-6109.2010.01996.x
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