HIV-1 viral infectivity factor interacts with TP53 to induce G2 cell cycle arrest and positively regulate viral replication

Viral infectivity factor, an accessory protein encoded in the HIV-1 genome, induces G2 cell cycle arrest; however, the biological significance and mechanism(s) remain totally unclear. Here we demonstrate that the TP53 pathway is involved in Vif-mediated G2 cell cycle arrest. Vif enhances the stabili...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Izumi, Taisuke, Io, Katsuhiro, Matsui, Masashi, Shirakawa, Kotaro, Shinohara, Masanobu, Nagai, Yuya, Kawahara, Masahiro, Kobayashi, Masayuki, Kondoh, Hiroshi, Misawa, Naoko, Koyanagi, Yoshio, Uchiyama, Takashi, Takaori-Kondo, Akifumi
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996458/
https://ncbi.nlm.nih.gov/pubmed/21071676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008076107
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares