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Gene Expression Network Reconstruction by Convex Feature Selection when Incorporating Genetic Perturbations

Cellular gene expression measurements contain regulatory information that can be used to discover novel network relationships. Here, we present a new algorithm for network reconstruction powered by the adaptive lasso, a theoretically and empirically well-behaved method for selecting the regulatory f...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Logsdon, Benjamin A., Mezey, Jason
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996324/
https://ncbi.nlm.nih.gov/pubmed/21152011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001014
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