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Gene Expression Network Reconstruction by Convex Feature Selection when Incorporating Genetic Perturbations
Cellular gene expression measurements contain regulatory information that can be used to discover novel network relationships. Here, we present a new algorithm for network reconstruction powered by the adaptive lasso, a theoretically and empirically well-behaved method for selecting the regulatory f...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996324/ https://ncbi.nlm.nih.gov/pubmed/21152011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001014 |
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