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Identifying Network Perturbation in Cancer
We present a computational framework, called DISCERN (DIfferential SparsE Regulatory Network), to identify informative topological changes in gene-regulator dependence networks inferred on the basis of mRNA expression datasets within distinct biological states. DISCERN takes two expression datasets...
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| 出版年: | PLoS Comput Biol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4856318/ https://ncbi.nlm.nih.gov/pubmed/27145341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004888 |
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