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Identifying Network Perturbation in Cancer
We present a computational framework, called DISCERN (DIfferential SparsE Regulatory Network), to identify informative topological changes in gene-regulator dependence networks inferred on the basis of mRNA expression datasets within distinct biological states. DISCERN takes two expression datasets...
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Publicado no: | PLoS Comput Biol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4856318/ https://ncbi.nlm.nih.gov/pubmed/27145341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004888 |
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