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Targeting TORC2 in multiple myeloma with a new mTOR kinase inhibitor
Although preclinical work with rapalogs suggests potential in treatment of multiple myeloma (MM), they have been less successful clinically. These drugs allostearically inhibit the mammalian target of rapamycin kinase primarily curtailing activity of the target of rapamycin complex (TORC)1. To asses...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996116/ https://ncbi.nlm.nih.gov/pubmed/20686120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-05-285726 |
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