Hypomethylation of the IGF2 DMR in Colorectal Tumors, Detected by Bisulfite Pyrosequencing, is Associated with Poor Prognosis

BACKGROUND & AIMS: The insulin-like growth factor 2 (IGF2) gene is normally imprinted. Constitutive loss of imprinting (LOI) of IGF2 has been associated with increased risks of colon cancer and adenoma, indicating its role in carcinogenesis. The conventional LOI assay relies on a germline polymo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Baba, Yoshifumi, Nosho, Katsuhiko, Shima, Kaori, Huttenhower, Curtis, Tanaka, Noriko, Hazra, Aditi, Giovannucci, Edward L., Fuchs, Charles S., Ogino, Shuji
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995815/
https://ncbi.nlm.nih.gov/pubmed/20682317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.07.050
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados