Novel Application of Structural Equation Modeling to Correlation Structure Analysis of CpG Island Methylation in Colorectal Cancer

The CpG island methylator phenotype (CIMP-high, CIMP1) is a distinct phenotype associated with microsatellite instability (MSI) and BRAF mutation in colon cancer. Recent evidence suggests the presence of KRAS mutation-associated CIMP subtype (CIMP-low, CIMP2). We used cluster analysis, principal com...

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Главные авторы: Tanaka, Noriko, Huttenhower, Curtis, Nosho, Katsuhiko, Baba, Yoshifumi, Shima, Kaori, Quackenbush, John, Haigis, Kevin M., Giovannucci, Edward, Fuchs, Charles S., Ogino, Shuji
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2010
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Regular Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993288/
https://ncbi.nlm.nih.gov/pubmed/21037082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100361
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