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ABCA1 and ABCG1 Protect Against Oxidative Stress–Induced Macrophage Apoptosis During Efferocytosis

RATIONALE: Antiatherogenic effects of plasma high-density lipoprotein (HDL) include the ability to inhibit apoptosis of macrophage foam cells. The ATP-binding cassette transporters ABCA1 and ABCG1 have a major role in promoting cholesterol efflux from macrophages to apolipoprotein A-1 and HDL and ar...

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Bibliografiske detaljer
Main Authors: Yvan-Charvet, Laurent, Pagler, Tamara A., Seimon, Tracie A., Thorp, Edward, Welch, Carrie L., Witztum, Joseph L., Tabas, Ira, Tall, Alan R.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995809/
https://ncbi.nlm.nih.gov/pubmed/20431058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.217281
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