Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes

BACKGROUND: Insulin resistance appears to be the best predictor of the development of diabetes in the children of patients with type 2 diabetes, but the mechanism responsible is unknown. METHODS: We performed hyperinsulinemic–euglycemic clamp studies in combination with infusions of [6,6-(2)H(2)]glu...

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Hlavní autoři: Petersen, Kitt Falk, Dufour, Sylvie, Befroy, Douglas, Garcia, Rina, Shulman, Gerald I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995502/
https://ncbi.nlm.nih.gov/pubmed/14960743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa031314
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