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Decreased Insulin-Stimulated ATP Synthesis and Phosphate Transport in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Parents

BACKGROUND: Insulin resistance is the best predictor for the development of type 2 diabetes. Recent studies have shown that young, lean, insulin-resistant (IR) offspring of parents with type 2 diabetes have reduced basal rates of muscle mitochondrial phosphorylation activity associated with increase...

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Detalhes bibliográficos
Main Authors: Petersen, Kitt F, Dufour, Sylvie, Shulman, Gerald I
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184227/
https://ncbi.nlm.nih.gov/pubmed/16089501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0020233
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