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Mechanism of N-methylation by the tRNA m(1)G37 methyltransferase Trm5
Trm5 is a eukaryal and archaeal tRNA methyltransferase that catalyzes methyl transfer from S-adenosylmethionine (AdoMet) to the N(1) position of G37 directly 3′ to the anticodon. While the biological role of m(1)G37 in enhancing translational fidelity is well established, the catalytic mechanism of...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2995409/ https://ncbi.nlm.nih.gov/pubmed/20980671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2376210 |
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