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A Divalent Metal Ion-Dependent N(1)-Methyl Transfer to G37-tRNA
The catalytic mechanism of the majority of S-adenosyl methionine (AdoMet)-dependent methyl transferases requires no divalent metal ions. Here we report that methyl transfer from AdoMet to N(1) of G37-tRNA, catalyzed by the bacterial TrmD enzyme, is strongly dependent on divalent metal ions and that...
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| 發表在: | Chem Biol |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4224600/ https://ncbi.nlm.nih.gov/pubmed/25219964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2014.07.023 |
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