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Maintenance of the DNA-Damage Checkpoint Requires DNA-Damage-Induced Mediator Protein Oligomerization

Oligomeric assembly of Brca1 C-terminal (BRCT) domain-containing mediator proteins occurs at sites of DNA damage. However, the functional significance and regulation of such assemblies are not well understood. In this study, we defined the molecular mechanism of DNA-damage-induced oligomerization of...

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Sonraí Bibleagrafaíochta
Main Authors: Usui, Takehiko, Foster, Steven S., Petrini, John H.J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995296/
https://ncbi.nlm.nih.gov/pubmed/19187758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.12.022
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