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Taking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response
The cellular DNA damage response (DDR) is activated by many types of DNA lesions. Upon recognition of DNA damage by sensor proteins, an intricate signal transduction network is activated to coordinate diverse cellular outcomes that promote genome integrity. Key components of the DDR in mammalian cel...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2725228/ https://ncbi.nlm.nih.gov/pubmed/19473886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.04.012 |
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