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The cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cells

Cohesin complexes mediate sister chromatid cohesion. Cohesin also becomes enriched at DNA double-strand break sites and facilitates recombinational DNA repair. Here, we report that cohesin is essential for the DNA damage-induced G2/M checkpoint. In contrast to cohesin's role in DNA repair, the...

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Autors principals: Watrin, Erwan, Peters, Jan-Michael
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738698/
https://ncbi.nlm.nih.gov/pubmed/19629043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.202
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