A chromosome 11-linked determinant controls fetal globin expression and the fetal-to-adult globin switch.
Hybrids formed by fusing mouse erythroleukemia (MEL) cells with human fetal erythroid cells produce human fetal globin, but they switch to adult globin production as culture time advances. To obtain information on the chromosomal assignment of the elements that control gamma-to-beta switching, we an...
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| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
1987
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299487/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3479779/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.22.8105 |
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