The membrane-spanning domain of gp41 plays a critical role in intracellular trafficking of the HIV envelope protein

BACKGROUND: The sequences of membrane-spanning domains (MSDs) on the gp41 subunit are highly conserved among many isolates of HIV-1. The GXXXG motif, a potential helix-helix interaction motif, and an arginine residue (rare in hydrophobic MSDs) are especially well conserved. These two conserved eleme...

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Autori principali: Miyauchi, Kosuke, Curran, A Rachael, Long, Yufei, Kondo, Naoyuki, Iwamoto, Aikichi, Engelman, Donald M, Matsuda, Zene
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994783/
https://ncbi.nlm.nih.gov/pubmed/21073746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-95
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