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Conserved arginine residue in the membrane-spanning domain of HIV-1 gp41 is required for efficient membrane fusion

Despite the high mutation rate of HIV-1, the amino acid sequences of the membrane-spanning domain (MSD) of HIV-1 gp41 are well conserved. Arginine residues are rarely found in single membrane-spanning domains, yet an arginine residue, R(696) (the numbering is based on that of HXB2), is highly conser...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Long, Yufei, Meng, Fanxia, Kondo, Naoyuki, Iwamoto, Aikichi, Matsuda, Zene
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875340/
https://ncbi.nlm.nih.gov/pubmed/21667332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1051-0
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