High affinity binding of hydrophobic and autoantigenic regions of proinsulin to the 70 kDa chaperone DnaK

BACKGROUND: Chaperones facilitate proper folding of peptides and bind to misfolded proteins as occurring during periods of cell stress. Complexes of peptides with chaperones induce peptide-directed immunity. Here we analyzed the interaction of (pre)proinsulin with the best characterized chaperone of...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Burkart, Volker, Siegenthaler, Rahel K, Blasius, Elias, Vandenbroeck, Koen, Alloza, Iraide, Fingberg, Waltraud, Schloot, Nanette C, Christen, Philipp, Kolb, Hubert
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994776/
https://ncbi.nlm.nih.gov/pubmed/21059249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-11-44
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares