The Autoantigenic Proinsulin B-Chain Peptide B11-23 Synergises with the 70 kDa Heat Shock Protein DnaK in Macrophage Stimulation

BACKGROUND: Heat shock proteins (Hsp) act as intracellular chaperones and in addition are used as adjuvant in vaccines of peptides complexed with recombinant Hsp. By interacting with autologous peptides, Hsp may promote the induction of autoimmune reactivity. OBJECTIVE: Here, we analysed whether the...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Diabetes Res
Päätekijät: Blasius, Elias, Gülden, Elke, Kolb, Hubert, Habich, Christiane, Burkart, Volker
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Hindawi 2018
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6304834/
https://ncbi.nlm.nih.gov/pubmed/30622969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4834673
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