Mechanism of epidermal growth factor receptor autophosphorylation and high-affinity binding.

Epidermal growth factor (EGF) receptor monomers and noncovalently associated dimers were isolated by sucrose density gradient centrifugation, and their respective binding and autophosphorylation activities were determined. We find that monomers are low-affinity receptors and dimers are high-affinity...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Böni-Schnetzler, M, Pilch, P F
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299411/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3500470/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.22.7832
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