Mechanism of epidermal growth factor receptor autophosphorylation and high-affinity binding.
Epidermal growth factor (EGF) receptor monomers and noncovalently associated dimers were isolated by sucrose density gradient centrifugation, and their respective binding and autophosphorylation activities were determined. We find that monomers are low-affinity receptors and dimers are high-affinity...
Gardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1987
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299411/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3500470/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.22.7832 |
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