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The Ca(2+) Channel TRPML3 Regulates Membrane Trafficking and Autophagy

TRPML3 is an inward rectifying Ca(2+) channel that is regulated by extracytosolic H(+). Although gain-of-function mutation in TRPML3 causes the varitint-waddler phenotype, the role of TRPML3 in cellular physiology is not known. Here, we report that TRPML3 is a prominent regulator of endocytosis, mem...

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Detalles Bibliográficos
Main Authors: Kim, Hyun Jin, Soyombo, Abigail A., Tjon-Kon-Sang, Sandra, So, Insuk, Muallem, Shmuel
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993507/
https://ncbi.nlm.nih.gov/pubmed/19522758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2009.00924.x
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