Palmitoylation controls trafficking of the intracellular Ca(2+) channel MCOLN3/TRPML3 to regulate autophagy

MCOLN3/TRPML3 is a Ca(2+)-permeable cation channel that is expressed in multiple subcellular compartments with dynamic localization. Our previous studies suggest that upon macroautophagy/autophagy induction MCOLN3/TRPML3 is recruited and provides Ca(2+) for the fusion process in autophagosome biogen...

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Publicado en:Autophagy
Autores principales: Kim, So Woon, Kim, Dong Hyun, Park, Kyoung Sun, Kim, Mi Kyung, Park, Yun Min, Muallem, Shmuel, So, Insuk, Kim, Hyun Jin
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2018
Materias:
Research Paper - Basic Science
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333453/
https://ncbi.nlm.nih.gov/pubmed/30215288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1518671
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